Buy Visine Classic eye drops 0.5 mg/ml 0.5 ml ampoule 10 pcs

Tetryzoline

Brand Laborator Uniter

In stock 786 Items

Available since: 2019-09-19

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Clinical Pharmacology

Visine is a sympathomimetic drug that stimulates the alpha adrenergic receptors of the sympathetic nervous system, but does not have or has a weak effect on beta-adrenergic receptors. Being a sympathomimetic amine, it has a vasoconstrictor effect and reduces tissue swelling.

The effect begins a few minutes after instillation and lasts 4-8 hours.

Pharmacokinetics

Indications

To relieve swelling and hyperemia of the conjunctiva (eye redness):

Caused by chemical and physical factors (smoke, wind, dust, chlorinated water, light, cosmetics, contact lenses).
Caused by allergic reactions such as pollinosis.

Composition

1 ml of eye drops contains:

Active substance:Tetryzolinee hydrochloride 0.50 mg.

Excipients:boric acid 12.30 mg, sodium tetraborate (borax) 0.25 mg, sodium chloride 2.23 mg, water for injection to 1 ml.

Tetryzoline is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Visine Classic	Laborator Uniter	France	eye drops
VisOptic	K.O.Romparm Company S.R.L	Romania	eye drops
MonteVisine	Hemofarm	Serbia	eye drops
Octilia®	S.I.F.I. S.p.A	Italy	eye drops
Visine	Keata Pharma Inc	Canada	eye drops

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Dosage and Administration

Adults and children over 3 years old are instilled 1-2 drops 2-3 times / day in the lower conjunctival sac of the affected eye.

If within 48 hours the improvement did not occur, the further use of the drug should be discontinued and consult a doctor.

Adverse reactions

Local reactions: increased intraocular pressure, burning sensation and reactive hyperemia of the eye; rarely - the expansion of the pupil.

Systemic reactions: increased blood pressure, hyperglycemia, impaired cardiac activity, headache, nausea, drowsiness, weakness, tremor, dizziness, insomnia, tachycardia, allergic reactions.

Contraindications

WITH caution the drug should be used for arterial hypertension, arrhythmia, aneurysm, hyperthyroidism, pheochromocytoma, diabetes mellitus, severe organic heart and vascular diseases (including CHD), as well as during treatment with MAO inhibitors and other drugs that increase blood pressure.

Drug interactions

Simultaneous use with MAO inhibitors, tricyclic antidepressants, guanetidinum can cause arterial hypertension, tachycardia.

Simultaneous use with reserpine, insulin, propranolol, general anesthetics, atropine increases the risk of cardiovascular effects of Tetryzoline.

Simultaneous use with guanethidine can provoke mydriasis with temporary visual impairment.

Pregnancy and Lactation

The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the intended benefit to the mother outweighs the risk to the fetus or child.

Special instructions

Visoptik appropriate to use only with mild eye irritation. If irritation and hyperemia of the conjunctiva are associated with an infectious disease, the presence of a foreign body or chemical corneal trauma, consult an eye specialist.

If within 48 hours after the start of the use of eye drops, the symptoms of the disease persist, become more pronounced or have side effects, you should stop using the drug and consult with an optometrist.

In case of intense pain in the eyes, headache, blurred vision, the sudden appearance of "floating spots" before the eyes, red eyes, pain when exposed to light or double vision in the eyes, you should immediately consult a doctor.

When wearing contact lenses they are removed before instillation of the drug and re-set 15 minutes after it. It is necessary to avoid direct contact of eye drops with soft contact lenses due to a possible violation of their transparency.

The drug should not be used simultaneously with MAO inhibitors (including phenelzine, nialamide, iproniazid) and for 10 days after stopping their administration.

Influence on ability to drive motor transport and control mechanisms

During the period of treatment, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration, psychomotor speed and good vision (after using eye drops, pupil dilation and blurred vision are possible).

Overdosage

The development of systemic symptoms of overdose is possible with the accidental or deliberate intake of the drug inside or overdosing with local use.

Symptoms: pupil dilation, nausea, cyanosis, fever, convulsions, arrhythmias, arterial hypertension, pulmonary edema, dyspnea. Excessive systemic absorption of imidazole derivatives can lead to CNS depression, accompanied by drowsiness, hypothermia, bradycardia, collapse, apnea, and coma.

The risk of overdose symptoms associated with the absorption of the drug is high in young children, especially if swallowed. Overdose in children can manifest depression of the central nervous system, accompanied by drowsiness, excessive sweating, severe hypotension, up to shock.

Treatment: they prescribe Activated charcoal, gastric lavage, oxygen inhalation, use of antipyretic and anticonvulsant drugs. Phentolamine 5 mg by 0.9% sodium chloride solution slowly IV or 100 mg orally is used to reduce blood pressure. The specific antidote is unknown.