Buy Troxerutin gel 2% 40 g
  • Buy Troxerutin gel 2% 40 g


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Clinical Pharmacology

Troxerutin - venotonic, angioprotective agent, bioflavonoid. Reduces the permeability and fragility of capillaries, strengthens the vascular wall, improves microcirculation, has anti-edema effect. Participates in redox processes, blocks cell hyaluronic acid. Increases the density of the vascular wall, reduces the exudation of the liquid part of the plasma and diapedes blood cells. Reduces inflammation in the vascular wall, limiting adhesion to its surface platelets.

The use of Troxerutin is possible both in the initial and in the late stages of the treatment of chronic venous insufficiency, it can be used as one of the components of the complex treatment.


Phlebeurysm; chronic venous insufficiency with such manifestations as edema, pain, heaviness in the lower limbs; surface thrombophlebitis, peripheral, phlebothrombosis; postthrombotic syndrome; post-traumatic edema, hematomas; prevention of complications after vein surgery; hemorrhoids.


100 g of gel contains the active substance: troxerutin - 2.0 g

Troxerutin is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Troxerutin Sopharma Bulgaria gel
Troxerutin Biochemist Saransk Russia gel
Troxerutin Ozon Russia gel
Troxerutin Ozon Russia capsules
Troxerutin Zentiva KS Czech capsules
Troxevasin Neo Balkanpharma Bulgaria gel
Troxevasin Balkanpharma Bulgaria capsules
Troxerutin VetProm AD Bulgaria gel
Troxerutin Sopharma Bulgaria capsules
Troxerutin-MIC Minskintercaps Belarus capsules
Troxerutin Vramed Bulgaria gel
Troxevasin Balkanpharma Bulgaria gel

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Dosage and Administration

Externally: the gel is applied evenly in a thin layer in the morning and evening on the skin over the painful area and lightly massaged until completely absorbed. The dose of the drug depends on the area of ​​the damaged surface, but should not exceed 3-4 cm of gel (1.5-2 g). The gel can be applied under the occlusive dressing.

Adverse reactions

In some cases, possible allergic reactions (skin rash).

With care: a renal failure (long use).

  • Brand name: Troxerutin
  • Active ingredient: Troxerutin
  • Dosage form: Gel for external use
  • Manufacturer: Sopharma

Studies and clinical trials of Troxerutin (Click to expand)

  1. Evaluation of the safety of a coumarin–troxerutin combination
  2. Spectroscopic studies on the interaction between troxerutin and bovine serum albumin
  3. Regioselective enzymatic acylation of troxerutin in nonaqueous medium
  4. The electrochemical oxidation of troxerutin and its sensitive determination in pharmaceutical dosage forms at PVP modified carbon paste electrode
  5. The simultaneous separation and determination of six flavonoids and troxerutin in rat urine and chicken plasma by reversed-phase high-performance liquid chromatography with ultraviolet–visible detection
  6. Ultrasound-promoted enzymatic synthesis of troxerutin esters in nonaqueous solvents
  7. Liquid chromatography/tandem mass spectrometry assay for the quantification of troxerutin in human plasma
  8. Prospektive, doppelblinde Therapiestudie zur Prophylaxe der Radioxerostomie durch Cumarin/Troxerutin bei Patienten mit Kopf-Hals-Karzinomen
  9. LC–MS–MS Determination of Troxerutin in Plasma and Its Application to a Pharmacokinetic Study
  10. Protection of cellular DNA from γ-radiation-induced damages and enhancement in DNA repair by troxerutin
  11. Treatment of the common cold with troxerutin
  12. NGF-Dependent Activation of TrkA Pathway: A Mechanism for the Neuroprotective Effect of Troxerutin in D-Galactose-Treated Mice
  13. One-electron redox reactions of troxerutin in aqueous solutions
  14. Troxerutin protects the isolated perfused rat liver from a possible lipid peroxidation by coumarin
  15. Aescin and troxerutin as a successful combination for the treatment of inner ear perfusion disturbances
  16. Chronic administration of troxerutin protects mouse kidney against d-galactose-induced oxidative DNA damage
  17. Troxerutin protects the mouse kidney from d-galactose-caused injury through anti-inflammation and anti-oxidation
  18. Chronic administration of troxerutin protects mouse brain against d-galactose-induced impairment of cholinergic system
  19. Troxerutin-carbazochrome combination versus placebo in the treatment of posthemorrhoidectomy symptoms: a single-center, randomized, double-blind, placebo-controlled study
  20. Homocysteine content of plasma in ischemic heart disease, the reducing effect of pyridoxine, folate, cobalamin, choline, riboflavin and troxerutin. Correction of a calculation error
  21. Protective Effects of Troxerutin on β-Amyloid (1-42)-Induced Impairments of Spatial Learning and Memory in Rats
  22. Erratum to: Protective Effects of Troxerutin on β-Amyloid (1-42)-Induced Impairments of Spatial Learning and Memory in Rats
  23. Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis

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