Tykveol
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Clinical Pharmacology
Tykveol - a complex preparation containing biologically active substances derived from pumpkin seeds.
The high content of tocopherols (alpha, beta, gamma, sigma isomers) and carotenoids has a pronounced antioxidant effect, which inhibits lipid peroxidation in biological membranes.
Essential phospholipids have a hepatoprotective effect, contribute to the restoration of the cell membrane of hepatocytes, its structure and function.
Essential fatty acids are involved in lipid metabolism, in the regulation of cholesterol and triglyceride metabolism, in the metabolism of arachidonic acid (as a biochemical precursor of prostaglandins).
The total set of pharmacological properties of biologically active substances in the drug Tykveol determines its anti-inflammatory and cytoprotective effects when applied topically.
Tykveol improves the functional state of the biliary tract, changing the chemical composition of bile, has a slight choleretic effect, reduces inflammation in the epithelium of the biliary system.
Tykveol, possessing antiandrogenic properties, reduces the proliferation of prostate gland cells, normalizes its function by improving microcirculation and anti-inflammatory action.
Indications
- chronic prostatitis;
- Benign prostatic hyperplasia stage I-II with associated prostatitis
Composition
1 rectal suppository contains: pumpkin seed oil 500 ml;
Excipients: cocoa butter or polyethylene glycol, emulsifier.
Tykveol is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Tykveol | Europe-Biopharm | Russia | rectal suppositories |
Tykveol | Europe Firm IPP | Russia | butter |
Tykveol | Europe-Biopharm | Russia | capsules |
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Dosage and Administration
Tykveol rectal suppositories injected into the rectum (pre-moistened with water) and 1 suppository 1-3 times / day.
The course of treatment ranges from 10 days to 3 months, or conduct short courses of treatment for 10-15 days for 6 months.
Adverse reactions
From the digestive system: rarely - dyspepsia, diarrhea.
Other: allergic reactions.
Contraindications
Hypersensitivity to the drug.
Drug interactions
Tykveol not prescribed in combination with antacids, histamine H blockers2receptors, bismuth preparations, proton pump blockers.
Pregnancy and Lactation
Clinical data on the efficacy and safety of Tykveol in pregnancy and lactation are not available.
Special instructions
In the case of side effects, it is necessary to reduce the dose of the drug.
Tykveol is used both as monotherapy and as part of complex therapy.
The drug is compatible with any food.
In inflammatory and degenerative processes of the mucous membrane of the upper gastrointestinal tract it is recommended to take Tykveol in the form of oil, avoid taking the drug in the form of capsules.
Use in Pediatrics
Clinical data on the efficacy and safety of the drug in children are not available.
Overdosage
Symptoms: diarrhea.
Treatment: It is necessary to reduce the dose of the drug.
- Brand name: Tykveol
- Active ingredient: Pumpkin ordinary seed oil
- Dosage form: Rectal suppositories.
- Manufacturer: Europe-Biopharm
- Country of Origin: Russia