Gaviscon®
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2019-09-19
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Clinical Pharmacology
Gaviscon® Double Action effectively relieves heartburn and digestive disorders: 1) quickly neutralizes excess gastric acid, 2) enters the stomach and interacts with its contents, forming a protective barrier (raft) that prevents heartburn.
When ingested, Gaviscon reacts quickly with the acidic contents of the stomach. This forms an alginate gel that prevents the occurrence of gastroesophageal reflux. With regurgitation, the gel is more likely than the contents of the stomach to enter the esophagus, where it reduces the irritation of the mucous membrane.
Pharmacokinetics
The mechanism of action of the drug Gaviscon does not depend on the absorption into the systemic circulation.
Indications
Symptomatic treatment of dyspepsia associated with increased acidity of gastric juice and gastroesophageal reflux (heartburn, sour belching); feeling of heaviness in the stomach after eating, including during pregnancy.
Composition
10 ml of suspension contains:
Active substances: sodium alginate 500 mg; sodium bicarbonate; calcium carbonate;
Excipients: carbomer; methyl parahydroxybenzoate; propyl parahydroxybenzoate; sodium saccharinate; peppermint oil; sodium hydroxide; purified water.
Gaviscon® is marketed under different brands and generic names, and comes in different dosage forms:
| Brand name | Manufacturer | Country | Dosage form |
|---|---|---|---|
| Gaviscon Double action | Reckitt Benckiser | UK | suspension |
| Gaviscon | Reckitt Benckiser | UK | pills |
| Gaviscon Double action | Reckitt Benckiser | UK | pills |
| Gaviscon Forte | Reckitt Benckiser | UK | tea bags |
| Gaviscon Double action | Reckitt Benckiser | UK | tea bags |
| Gaviscon Forte | Reckitt Benckiser | UK | suspension |
| Gaviscon | Reckitt Benckiser | UK | suspension |
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Dosage and Administration
For oral use. Adults and children over 12 years old: 10 - 20 ml after meals and before bedtime (up to 4 times a day). The maximum daily dose is 80 ml. For elderly patients, dose change is not required. Do not use the drug for a long time, if after 7 days of taking the drug symptoms persist, you must consult a doctor to review the therapy.
Adverse reactions
Allergic reactions are possible.
Contraindications
Hypersensitivity to any of the components of the drug, renal failure, moderate and severe severity, children under 12 years.
Carefully:
If you have the following diseases or conditions, you should consult a doctor before using the drug: hypercalcemia, nephrocalcinosis, urolithiasis with the formation of calcium oxalate stones (see section "Specific instructions"), congestive heart failure (see section "Specific instructions"), hypophosphatemia , renal failure mild severity (see "Special instructions").
Pregnancy and Lactation
Maybe.
Special instructions
The sodium content in 10 ml of the suspension is 141 mg (6.2 mmol). This should be considered when it is necessary to follow a diet with a limited salt content, for example, in some cases of congestive heart failure and in cases of impaired renal function.
In the absence of improvement in symptoms within 7 days, you should consult with your doctor.
Overdosage
Symptoms: bloating may occur.
Treatment: symptomatic therapy.
- Brand name: Gaviscon
- Active ingredient: Sodium alginate, Sodium bicarbonate, Calcium carbonate
- Manufacturer: Reckitt Benckiser
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