Buy Nitrospray ICN spray 0.4 mg/dose 10 ml

Nitroglycerine

Brand Pharmstandard

In stock 1284 Items

Available since: 2019-09-19

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Clinical Pharmacology

Antianginal Nitrospray-ICN expands veins and arteries, reduces pre-and afterload, OPSS. It improves coronary blood flow and redistributes it in favor of ischemic myocardial areas, reduces heart function. Inhibits aggregation and platelet adhesion.

Indications

Angina pectoris (stopping and prevention of attacks), acute myocardial infarction and acute left ventricular failure (complex therapy).

Composition

100 ml of spray contain nitroglycerin 1 g.

Nitroglycerine is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Nitrospray ICN	Pharmstandard	Russia	spray
Nitroglycerine	Pharmstandard	Russia	pills
Perlinganit	UCB Pharma	Belgium	ampoules
Nitroglycerine	Medisorb	Russia	spray
Nitroglycerine	Medisorb	Russia	pills
Nitroglycerine	Lumy	Russia	capsules
Nitrocore	Pharmstandard	Russia	pills
Nitromint	Egis	Hungary	spray

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Dosage and Administration

Nitrospray-ICN is taken sublingually, in a sitting position, amid breath holding. Relief of angina pectoris: 1-2 doses, containing 0.4-0.8 mg of nitroglycerin (if necessary, again, no less than 30 seconds), a maximum of 3 doses at intervals of 5 minutes. Prevention of angina attacks: 1 dose for 5-10 minutes before the intended load or stress. The maximum single dose - 1.6 mg (4 doses), daily - 6.4 mg (16 doses).

Adverse reactions

From the nervous system and sensory organs: headache, dizziness, weakness, blurred vision, motor anxiety. From the cardiovascular system and blood (hematopoiesis, hemostasis): arterial hypotension, reflex tachycardia, increased symptoms of angina (rare). From the side Organs of the digestive tract: nausea, vomiting, dry mouth. On the skin side: facial flushing, dermatitis, rash.

Contraindications

Hypersensitivity, shock, collapse, acute myocardial infarction with low filling pressure of the left ventricle, arterial hypotension (below 90 mmHg), hypertrophic cardiomyopathy, hemorrhagic stroke, head injury, toxic pulmonary edema, closed-angle glaucoma.

Drug interactions

Other antihypertensive drugs, antidepressants, PDE inhibitors (sildenafil), ethanol may enhance the hypotensive effect of Nitrospray. At the same time, the effectiveness of nitrospray may decrease.
With simultaneous use with nitrospray, a decrease in the anticoagulant effect of heparin is possible.

Special instructions

Care must be taken when abruptly moving to a vertical position from a “lying” or “sitting” position, prolonged standing, exercise, and hot weather (orthostatic reactions are possible).

Overdosage

Symptoms: cyanosis of the lips, nails, palms, dizziness, fainting, feeling of strong pressure in the head, shortness of breath, unusual tiredness or weakness, weak and rapid heartbeat, fever, cramps.
Treatment: transfer of the patient to the prone position with raised legs, carrying out symptomatic and supportive therapy.