Antistax®
Boehringer Ingelheim
536 Items
2019-09-19
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Clinical Pharmacology
Antistax-reducing capillary permeability, angioprotective.
Pharmacodynamics
Extract from red leaves of grapes contains pharmacologically active flavonoids, the main of which are quercetin-glucuronide and isoquercetin. The drug has a protective effect on the vascular epithelium (stabilizes membranes) and increases the elasticity of blood vessels (normalizes vascular permeability). Reducing the permeability of the vascular wall to plasma, proteins or water from the vessels into the surrounding tissue slows down the formation of new edemas and reduces existing ones.
Indications
Prevention and symptomatic treatment of chronic venous insufficiency (in combination with varicose veins), including edema of the lower limbs, feeling of heaviness and fatigue in the lower limbs, feeling of tension, paresthesia (change in sensitivity) and pain.
Composition
1 capsule contains:
Active substance: Inograd red leaves dry extract - 180 mg.
Excipients: silicon colloidal anhydrous oxide - 9.35 mg; dextrose (dry glucose syrup) - 38.25 mg; corn starch - 8.4 mg; magnesium stearate - 2.6 mg; talc - 8.4 mg; theoretical mass of capsule contents - 247 mg.
Capsule shell: gelatin - 63,004 mg; sodium dodecyl sulfate - 0.152 mg; purified water - 11.02 mg; titanium dioxide - 0.76 mg; ferric oxide hydrate (E171) (ferric oxide yellow) - 0.152 mg; ferric oxide (E172) (ferric oxide red) - 0.912 mg.
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Dosage and Administration
Orally, swallowing whole, drinking water, before meals, in the morning. The recommended dose for adults is 2 capsules per day. May increase the dose to 4 capsules per day.
Adverse reactions
Allergic reactions.
Contraindications
Hypersensitivity to the components of this drug.
Drug interactions
Not found.
Pregnancy and Lactation
Antistax® is not recommended to be taken during pregnancy and during breastfeeding (studies on the safety of the drug in pregnant and lactating women have not been conducted).
Special instructions
In case of insufficient or unsatisfactory symptomatic effect within 6 weeks of treatment, the patient should be advised to consult with a physician regarding other possible causes of edema.
Overdosage
No cases of overdose or intoxication were reported.
- Brand name: Antistax
- Active ingredient: Grape red leaf dry extract
- Dosage form: Capsules
- Manufacturer: Boehringer Ingelheim
- Country of Origin: Austria
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