Buy Capoten pills 25 mg, 56 pcs
  • Buy Capoten pills 25 mg, 56 pcs


801 Items
Dosage form
Brand & Manufacturer
Package Size
  • done All payments are SSL encrypted
  • done Full Refund if you haven't received your order
  • done International shipping to the USA, UK and Europe

Clinical Pharmacology

Competitive ACE inhibitor - an enzyme that promotes the conversion of angiotensin I to angiotensin II.
Kapoten has an antihypertensive effect, reduces round congestion (afterload), preload and resistance in the pulmonary vessels; increases heart volume and exercise tolerance.
With prolonged use reduces the severity of left ventricular myocardial hypertrophy, prevents the progression of heart failure and slows down the development of left ventricular dilatation.


- arterial hypertension (as monotherapy and in combination with other antihypertensive drugs, for example, with thiazide diuretics);
- chronic heart failure (as part of combination therapy);
- IHD (left ventricular dysfunction after myocardial infarction in patients in a stable clinical condition);
- diabetic nephropathy (microalbuminuria> 30 mg / day) for insulin-dependent diabetes mellitus.


1 tablet contains captopril 25 mg.

Excipients: lactose, corn starch, microcrystalline cellulose, stearic acid.

Captopril is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Capoten Akrikhin Russia pills
Captopril Pharmacor Production Russia pills
Captopril Sandoz Switzerland pills
Captopril-STI AVVA RUS Russia pills
Captopril Ozon Russia pills

No customer reviews for the moment.

Write your review

Write your review


Dosage and Administration

Doses of Capoten should be selected by a doctor. Inside, one hour before meals, 25-50 mg 2-3 times a day (but not more than 450 mg per day), for children the initial dose is 0.15-0.3 mg / kg (but not more than 6 mg / kg per day).

Adverse reactions

Since the cardiovascular system: orthostatic hypotension, tachycardia, peripheral edema.
On the part of the respiratory system: dry cough, bronchospasm, pulmonary edema.
Allergic reactions: angioedema of the extremities, face, lips, mucous membranes, tongue, pharynx or larynx.
From the water and electrolyte balance: hyperkalemia (most likely with renal failure), hyponatremia (most often with a salt-free diet and simultaneous use of diuretics.
From the urinary system: proteinuria, an increase in the content of urea nitrogen and creatinine in the blood plasma, acidosis.
From the hemopoietic system: in rare cases - neutropenia, agranulocytosis, thrombocytopenia and anemia, a positive test for antibodies to the nuclear antigen. In patients with normal renal function (QC less than 1.6 mg / dL) in the absence of other complicating factors, neutropenia was observed in 0.02% of cases.
From the digestive system: reversible and usually self-impaired taste, dry mouth, aphthous stomatitis; rarely - abdominal pain, diarrhea, gingival hyperplasia, hepatitis, elevated levels of liver transaminases in the blood plasma, hyperbilirubinemia.
Dermatological reactions: maculo-papular rash, usually accompanied by itching and, in rare cases, fever; hyperemia, vesicular or bullous eruptions, erythema (including Stevens-Johnson syndrome), photosensitization.
From the side of the central nervous system and peripheral nervous system: headache, dizziness, ataxia, paresthesias, drowsiness, visual disturbances.


- Quincke edema (hereditary or associated with the use of ACE inhibitors in history);
- pronounced impaired renal function;
- severe liver dysfunction;
- hyperkalemia;
- bilateral renal artery stenosis or arterial stenosis of a single kidney with progressive azotemia;
- condition after kidney transplantation;
- Aortic stenosis and similar obstructive changes that impede the flow of blood from the left ventricle;
- pregnancy;
- lactation period (breastfeeding);
- hypersensitivity to the drug and other ACE inhibitors.

Drug interactions

Diuretics, vasodilators, ganglioblockers, adrenergic blockers with simultaneous use enhance the antihypertensive effect of the drug Capoten.
Indomethacin and other NSAIDs, as well as clonidine, can reduce the antihypertensive effect of the drug Capoten.
Against the background of the simultaneous use of Capoten with allopurinol and procainamide, neutropenia and / or Stevens-Johnson syndrome may be observed, but the causal relationship of these phenomena is not clear.
With simultaneous use of immunosuppressants (eg, azathioprine and cyclophosphamide) with Capoten, the risk of hematological disorders increases.
Against the background of simultaneous use of probenecid, captopril excretion with urine is reduced.
The simultaneous use of salts of lithium and Capoten can lead to an increase in the concentration of lithium in the blood serum. This increases the risk of side effects and toxic effects of lithium preparations.
Simultaneous use of Capoten with potassium-sparing diuretics (triamterene, amiloride, and spironolactone) or potassium preparations may lead to hyperkalemia.

Special instructions

Caution should be given to Capoten for collagenoses due to the increased risk of neutropenia and agranulocytosis.
In the appointment of the drug to patients with severe disorders of water and electrolyte balance should carry out the correction of this condition.During treatment with Capoten, it is not recommended to take potassium-sparing diuretics or potassium preparations, especially for patients with severe impaired renal function.
Angioedema of the extremities, face, lips, mucous membranes, tongue, pharynx, or larynx is observed in patients using ACE inhibitors, including captopril. If the swelling is limited to the face and lips, this condition usually disappears after discontinuation of the drug. Antihistamines may be used to alleviate the clinical symptoms. Patients should be under the supervision of a physician until the symptoms disappear. If the edema covers the tongue, pharynx, or larynx with the threat of airway obstruction, a subcutaneous solution of 0.5 ml of 0.1% epinephrine solution should be injected.
During treatment with Capoten, low-sodium diets are indicated.
Kapoten can cause a false positive reaction when analyzing urine for acetone.
Use in Pediatrics
Safety and efficacy of the drug in children have not been studied.


Symptoms: pronounced decrease in blood pressure.
Treatment: effective administration of plasma-substituting drugs and hemodialysis.

  • Brand name: Capoten
  • Active ingredient: Captopril
  • Dosage form: Pills.
  • Manufacturer: Akrikhin
  • Country of Origin: Russia

Studies and clinical trials of Captopril (Click to expand)

  1. Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma
  2. HPLC Determination of Captopril in Human Plasma and Its Pharmacokinetic Study
  3. Narrow-bore liquid chromatography coupled to chemiluminescence detection for the analysis of pharmaceutical preparations containing hydrochlorothiazide and captopril
  6. Angiotensin converting enzyme inhibitor captopril does not prevent acute gastrointestinal radiation damage in the rat
  7. Flow Injection Chemiluminescence Determination of Captopril with In Situ Electrogenerated Mn3+ as the Oxidant
  8. Parafac and PLS Applied to Determination of Captopril in Pharmaceutical Preparation and Biological Fluids by Ultraviolet Spectrophotometry
  9. Captopril, a specific inhibitor of angiotensin converting enzyme, enhances both trypsin and vitellogenin titers in the grey fleshfly Neobellieria bullata
  10. The angiotensin converting enzyme inhibitor captopril reduces oviposition and ecdysteroid levels in Lepidoptera
  11. Reversal of Scleroderma Renal Crisis for More Than Two Years in a Patient Treated with Captopril
  12. Development of antinuclear antibody in patients treated with high doses of captopril
  13. Hypertensive crisis in systemic sclerosis: treatment with the new oral angiotensin converting enzyme inhibitor mk 421 (enalapril) in captopril-intolerant patients
  14. autoantibodies during captopril treatment
  15. Flow injection chemiluminescence determination of captopril based on its enhancing effect on the luminol–ferricyanide/ferrocyanide reaction
  16. Assay of free captopril in human plasma as monobromobimane derivative, using RPLC/(+)ESI/MS/MS: validation aspects and bioequivalence evaluation
  17. Determination of captopril in biological samples by high-performance liquid chromatography with ThioGlo™3 derivatization
  18. Simultaneous determination of captopril and S-benzoyl captopril in human blood by capillary gas chromatography–mass selective detection
  19. Captopril protects mice bone marrow cells against genotoxicity induced by gamma irradiation
  20. ChemInform Abstract: Probing the Importance of Spacial and Conformational Domains in Captopril Analogues for Angiotensin Converting Enzyme Activity.
  21. A Synthesis of Captopril Through a Baylis—Hillman Reaction.
  22. Binding Interaction of Captopril with Metal Ions: A Fluorescence Quenching Study
  23. Effective Controlled Release of Captopril by Silylation of Mesoporous MCM-41

Customers who bought this product also bought:

8 other products in the same category: