Licorice roots
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Clinical Pharmacology
Expectorant of plant origin
Indications
Used in adults and children as an expectorant for diseases of the upper respiratory tract, accompanied by cough, mainly in the presence of poor discharge, thick and viscous secretion (especially in children and the elderly).
Composition
Composition per 100 g of the drug
Active ingredient
Licorice extract thick with glycyrrhizic acid content in terms of dry matter 19.0% - 4 g
Excipients
Sugar (sucrose) -55 g
Purified water -31 g
Ethyl alcohol 90% (ethanol) - 10g.
Licorice roots is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Licorice root syrup | Caucasus flora | Russia | syrup |
Kashlestop | Bagheera | Russia | syrup |
Licorice root | Phytopharm Klenka AO | Poland | Other |
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Dosage and Administration
Adverse reactions
Allergic reactions are possible; in some cases dyspeptic symptoms (diarrhea) may occur. With prolonged use possible hypokalemia, increased blood pressure, the appearance of peripheral edema due to impaired water-salt metabolism.Contraindications
Increased individual sensitivity to the components of the drug, sucrase / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, pregnancy, breastfeeding, bronchial asthma, gastritis, gastric ulcer and duodenal ulcer during the exacerbation period.Drug interactions
Drug interactionSpecial instructions
Overdosage
When using the drug in doses higher than recommended, it is possible to increase the dose-related side effects.
- Brand name: Licorice root syrup
- Active ingredient: Licorice roots
- Dosage form: Thick homogeneous liquid from light brown to dark brown color with a characteristic odor.
- Manufacturer: Caucasus flora
Studies and clinical trials of Licorice roots (Click to expand)
- No teratogenic effect of prenoxdiazine: A population-based case–control study
- Phenolics with PPAR-γ Ligand-Binding Activity Obtained from Licorice (Glycyrrhiza uralensis Roots) and Ameliorative Effects of Glycyrin on Genetically Diabetic KK-Ay Mice.
- Preparation of Glycyrrhizic Acid (I) and Its Practically Useful Salts from the Commercial Licorice Roots Extract.
- Metabolic effects of licorice roots (Glycyrrhiza glabra) on lipid distribution pattern, liver and renal functions of albino rats
- Use of nano-liquid chromatography for the analysis of glycyrrhizin and glycyrrhetic acid in licorice roots and candies
- A novel process for extraction of natural sweetener from licorice (Glycyrrhiza glabra) roots
- Effects of glycyrrhizin, an active component of licorice roots, on Candida albicans infection in thermally injured mice
- Effects of chalcones isolated from licorice roots on leukotriene biosynthesis in human polymorphonuclear neutrophls
- Effects of flavonoids isolated from licorice roots (Glycyrrhiza inflata Bat.) On degranulation in human polymorphonuclear neutrophils
- Effects of flavonoids from licorice roots (Glycyrrhiza inflata Bat.) On arachidonic acid metabolism and aggregation in human platelets
- An on-membrane quantitative analysis system for glycyrrhizin in licorice roots and traditional Chinese medicines
- The Effect of Dry Cleared Extract from Licorice Roots on the Learning of Ovariectomized Rats
- Isolation and biological activity of lipids from licorice (Glycyrrhiza glabra) roots
- Inhibitory activity of diacylglycerol acyltransferase by glabrol isolated from the roots of licorice
- Phenolics with PPAR-γ ligand-Binding activity obtained from licorice (Glycyrrhiza uralensis Roots) and ameliorative effects of glycyrin on genetically diabetic KK-Ay mice
- Extraction of nutraceutical compounds from licorice roots with subcritical water
- Assessment of squalene synthase and beta-amyrin synthase gene expression in licorice roots treated with methyl jasmonate and salicylic acid using real-time qPCR
- ChemInform Abstract: Chemical Studies of Chinese Licorice-Roots. Part 1. Elucidation of Five New Flavonoid Constituents from the Roots of Glycyrrhiza glabra L. Collected in Xinjiang.
- Investigation of the repercolation process during the extraction of the roots and rootstocks of the Ural licorice
- Comparative metabolite profiling and fingerprinting of medicinal licorice roots using a multiplex approach of GC–MS, LC–MS and 1D NMR techniques
- Antioxidant Constituents from Licorice Roots: Isolation, Structure Elucidation and Antioxidative Capacity Toward LDL Oxidation
- Effect of licorice roots on carrageenan-induced decrease in immune complexes clearance in mice
- Permeability of the flavonoids liquiritigenin and its glycosides in licorice roots and davidigenin, a hydrogenated metabolite of liquiritigenin, using human intestinal cell line Caco-2
- Glabrol, an acyl-coenzyme A: Cholesterol acyltransferase inhibitor from licorice roots
- Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues