- done All payments are SSL encrypted
- done Full Refund if you haven't received your order
- done International shipping to the USA, UK and Europe
Pyrantel - antihelminthic.
Blocks neuromuscular transmission in sensitive worms.
It acts on helminths in the early phase of development and on mature forms, does not affect the larvae in the migration stage. Active against Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Trichostrongylus orientalis, Trichostrongylus colubriformis.
Practically not absorbed in the digestive tract. After ingestion in a single dose of 10 mg / kg body weight Cmaxis 0.005–0.13 mcg / ml and is achieved within 1–3 hours. Partially metabolized in the liver to N-methyl-1,3-propanediamine. It is excreted in feces (50% of the dose taken - unchanged) and with urine (about 7% - unchanged and as a metabolite).
Enterobiasis, ascariasis, hookworm, necatoriasis.
1 tablet contains:
Active ingredient: Pyrantel 250 mg;
Excipients: starch, gelatin, acacia gum, methyl parahydroxybenzoate, propyl parahydroxybenzoate, sodium carboxymethyl starch, talc, magnesium stearate, colloidal silicon dioxide (aerosil).
Pyrantel is marketed under different brands and generic names, and comes in different dosage forms:
|Brand name||Manufacturer||Country||Dosage form|
|Pyrantel||Oxford Laboratories Pvt. Ltd||India||suspension|
No customer reviews for the moment.
Dosage and Administration
Inside Dose and frequency of administration set individually, depending on the evidence, age and body weight of the patient.
In case of ascariasis and enterobiasis, a single dose of 10 mg / kg is prescribed: for adults and children over 12 years old - 750 mg (for body mass more than 75 kg - 1 g); children from 6 months to 2 years old - 125 mg, 2-6 years old - 250 mg, 6-12 years old - 500 mg. To avoid self-invasion, it was recommended to repeat the course 3 weeks after the first dose.
With hookworm - 10 mg / kg in 1 reception for 3 days.
For necatoriasis (severe forms) - 20 mg / kg / day for 2 days.
With isolated ascariasis - 5 mg / kg once.
Chewable pills before swallowing.
From the nervous system and sensory organs: rarely - headache, dizziness, drowsiness, insomnia, weakness; in some cases - hearing loss, hallucinations, confusion, paresthesia.
On the part of the digestive tract: nausea, vomiting, diarrhea, stomach pain; rarely - increased activity of hepatic transaminases.
Other: skin rash, fever.
Pregnancy and Lactation
Pyrantel is contraindicated for use in pregnancy.
If necessary, use during lactation should decide on the termination of breastfeeding.
When enterobiasis should be the simultaneous treatment of co-residents. After completion of treatment it is necessary to conduct a control study of feces on the eggs of the worm.
- Active ingredient: Pyrantel
- Bioequivalence of pyrantel pamoate dosage forms in healthy human subjects
- Spectrophotometric determination of pyrantel in pyrantel pamoate bulk samples and pharmaceutical formulations
- The comparative metabolism of pyrantel in five species
- Ion-selective membrane electrodes for the determination of pyrantel with low protein interference
- The treatment of Fasciolopsis buski infection in children: a comparison of thiabendazole, mebendazole, levamisole, pyrantel pamoate, hexylresorcinol and tetrachloroethylene
- Synthesis and nematocidal activities of new analogs of pyrantel
- Resistance of Oesophagostomum spp. in pigs to pyrantel citrate
- Determination of the efficacy of pyrantel pamoate at the therapeutic dose rate against the tapeworm Anoplocephala perfoliata in equids using s modification of the critical test method
- A dose-response investigation on the level of resistance to pyrantel citrate in nodular worms of pigs
- Effect of early season ivermectin and pyrantel treatments on strongylid infections in young Shetland ponies in The Netherlands
- Efficacy of an ivermectin/pyrantel pamoate chewable formulation against the canine hookworms, Uncinaria stenocephala and Ancylostoma caninum
- Efficacy of pyrantel tartrate against experimental infections with Haemonchus contortus, Teladorsagia circumcincta and Trichostrongylus colubriformis in goats
- Controlled efficacy study of the bioequivalence of strongid® C and generic pyrantel tartrate in horses
- Comparison of daily and monthly pyrantel treatment in yearling Thoroughbreds and the protective effect of strategic medication of mares on their foals
- Adsorption of pyrantel pamoate on mercury from aqueous solutions: Studies by stripping voltammetry
- Synergic effect of metronidazole and pyrantel pamoate on Giardia lamblia
- Clinical field efficacy and safety of pyrantel pamoate paste (19.13% w/w pyrantel base) against Anoplocephala spp. in naturally infected horses
- Comparative effects of milbemycin oxime-based and febantel–pyrantel embonate-based anthelmintic tablets on Toxocara canis egg shedding in naturally infected pups
- Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses
- Cyathostomes in horses in Canada resistant to pyrantel salts and effectively removed by moxidectin
- Macrocyclic lactone-resistant Parascaris equorum on stud farms in Canada and effectiveness of fenbendazole and pyrantel pamoate
- High-level pyrantel resistance in the hookworm Ancylostoma caninum
- Cases of reduced cyathostomin egg-reappearance period and failure of Parascaris equorum egg count reduction following ivermectin treatment as well as survey on pyrantel efficacy on German horse farms
- Field evaluation of the efficacy and the safety of a combination of oxantel/pyrantel/praziquantel in the treatment of naturally acquired gastrointestinal nematode and/or cestode infestations in dogs in Europe