Gastal®
Teva
1643 Items
2019-09-19
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Clinical Pharmacology
Gastal reduces the high level of acidity of gastric juice to normal levels and eliminates digestive disorders. The drug also inhibits the action of pepsin, bile enzymes (lecithin) and bile acids, promotes the rapid healing of gastric ulcers and protects the mucosa from aggressive factors (stimulates the secretion of mucus and alkaline sodium bicarbonate, epidermal growth factor, increases the concentration of phospholipids, etc.). The effect of the drug occurs immediately after administration and lasts another 2 hours. The drug is not absorbed inside, but is excreted in the feces.
Indications
According to indications for Gastal, it is taken for: gastritis with high acidity, ulcers of the stomach and small intestine, heartburn, erosions of the gastric mucosa, reflux esophagitis, diaphragmatic hernia, acute pancreatitis, with dyspepsia with a long delay of food in the stomach. Gastal is also indicated for the prevention of peptic ulcer disease.
Composition
The pills are white, round, with a flat and smooth surface and beveled edges.
1 tablet contains:
aluminum hydroxide-magnesium carbonate gel -450 mg
Excipients: mannitol, sorbitol, lactose, corn starch, sodium cyclamate, sodium saccharinate, talc, magnesium stearate, peppermint flavoring (peppermint).
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Dosage and Administration
The drug is taken orally. The tablet should be gradually dissolve (do not swallow it entirely).
Adults appoint 1-2 tab. 4-6 times a day, but not more than 8 tab. within 24 hours. The drug is recommended to be taken 1 hour after a meal and before bedtime.
The maximum duration of admission - 2 weeks.
Withheartburn the drug is prescribed in recommended doses, regardless of the meal.
For the purpose of prophylaxis, Gastal® is used before the intended irritant effect on the gastrointestinal mucosa.
For children aged 6 to 12 years prescribed half the dose for adults.
Adverse reactions
On the part of the digestive system: rarely (at least 0.01%, but less than 0.1%) - nausea, constipation, diarrhea, change in taste.
Other: in exceptional cases - allergic reactions.
Contraindications
- renal failure severe;
- Alzheimer's disease;
- hypophosphatemia;
- lactose intolerance, lactase deficiency or glucose-galactose malabsorption;
- children's age up to 6 years;
- hypersensitivity to salts of aluminum, magnesium or other components of the drug.
WITHcautionthe drug should be used in chronic renal failure, during pregnancy and during breastfeeding, in adults and children over 12 years old with a body weight less than 50 kg, in children aged 6 to 12 years, in elderly patients.
Drug interactions
The interval between taking Gastal and other medicines should be 1-2 hours.
Gastal® enhances the action of levodopa and nalidixic acid.
With a simultaneous use of the language, it is able to reduce the amount of time it takes to work on the website. barbiturates.
M-holinoblokatory, slowing gastric emptying, increase and prolong the effect of the drug.
Pregnancy and Lactation
Use of the drug during pregnancy and lactation (breastfeeding) is possible only under the supervision of a physician in cases where the intended benefit to the mother outweighs the potential risk to the fetus.
Special instructions
In patients with low body weight and in children over the age of 6 years, Gastal® should be used in smaller doses and less long.
In patients with impaired renal function, it is not recommended to use Gastal® in doses exceeding the recommended and for a longer time.
Continuous reception for more than 2 weeks is possible only with the appointment of a doctor.
Overdosage
Symptoms of acute overdose are not described.
Symptoms: long-term intake in high doses of drugs containing aluminum and magnesium may develop hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnemia, hyperaluminemia, encephalopathy, nephrocalcinosis and impaired kidney function. Possible increased side effects from the digestive system (constipation, diarrhea). In patients with renal insufficiency, thirst, a decrease in blood pressure, and hyporeflexia are possible.
Treatment: symptomatic therapy.
- Brand name: Gastal
- Active ingredient: Hydrotalcite, Magnesium hydroxide
- Manufacturer: Teva
- Country of Origin: Israel
Studies and clinical trials of Gastal (Click to expand)
- Co-occurrence of chronic physical pain and psychiatric morbidity in a community sample of older people
- Gastro-esophageal reflux disease confined to the sphincter
- Carbon partitioning in forage crops
- A prevalence study of current tobacco smoking in later life community and its association with sociodemographic factors, physical health and mental health status
- Dissolving efficacy of organic solvents on root canal sealers
- How much do water deficits alter the nitrogen nutrition status of forage crops?
- Responses of plant traits of four grasses from contrasting habitats to defoliation and N supply
- The effect of nitrogen fertilization upon the herbage production of tall fescue swards continuously grazed with sheep. 1. Herbage growth dynamics
- Assessment of the nitrogen status of grassland
- Quantitative trait loci for leaf length in perennial ryegrass (Lolium perenne L.)
- Relationships between nitrogen uptake and carbon assimilation in whole plants of tall fescue
- Temporal Relationships and Repeatability of Follicle Diameters and Hormone Concentrations within Individuals in Mares
- Follicle Deviation in Ovulatory Follicular Waves with One or Two Dominant Follicles in Mares
- Nuclear Configuration, Spindle Morphology and Cytoskeletal Organization of In Vivo Maturing Horse Oocytes
- Development of One vs Multiple Ovulatory Follicles and Associated Systemic Hormone Concentrations in Mares
- Effect of hCG in the Presence of hCG Antibodies on the Follicle, Hormone Concentrations, and Oocyte in Mares
- Effect of Suppression of FSH with a GnRH Antagonist (Acyline) Before and During Follicle Deviation in the Mare
- Chronology of the Barrett's metaplasia–dysplasia–carcinoma sequence
- Shared Sampling for Real-Time Alpha Matting
- Temperature effects on partitioning of 14C assimilates in tall fescue (Festuca arundinacea Schreb.)
- A functional–structural model of elongation of the grass leaf and its relationships with the phyllochron
- Manometry of the Lower Esophageal Sphincter: Inter- and Intraindividual Variability of Slow Motorized Pull-Through Versus Station Pull-Through Manometry
- N uptake and distribution in crops: an agronomical and ecophysiological perspective
- CT scanning of paranasal sinuses, test for airway hyperresponsiveness to carbachol and 24-HR esophageal PH monitoring are mandatory in the differential diagnosis of chronic cough
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