Buy Grammidin® spray 0.03 mg + 0.1 mg/dose 112 doses 1 pc.
  • Buy Grammidin® spray 0.03 mg + 0.1 mg/dose 112 doses 1 pc.

Grammidin®

1228 Items
2019-09-19
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$29.69
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Clinical Pharmacology

Combined drug for the treatment of infectious and inflammatory diseases of the throat and oral cavity.

The preparation contains the antimicrobial agent gramicidin C and the antiseptic agent cetylpyridinium chloride. The mechanism of action of gramicidin C is associated with an increase in the permeability of the cytoplasmic membrane of the microbial cell, which violates its stability and causes death. Gramicidin C has an antibacterial effect against a wide range of gram-positive and gram-negative microorganisms. Cetylpyridinium chloride is an antiseptic, inhibits the growth and reproduction of pathogens of infectious diseases of the oral cavity and throat. The drug has an antimicrobial effect, reduces inflammation, alleviates unpleasant sensations in the throat, facilitates swallowing.

Pharmacokinetics:

The drug is a local action. According to preclinical studies of pharmacokinetics, absorption is practically absent.

Indications

Infectious and inflammatory diseases of the mouth and throat: pharyngitis, tonsillitis, periodontitis, gingivitis, stomatitis.

Composition

1 dose:

gramicidin C dihydrochloride 0.0638 mg, which corresponds to the content of gramicidin C 0.03 mg, cetylpyridinium chloride 0.1 mg

Excipients: ethanol 96% - 9.5 mg, sucralose - 0.2 mg, glycerol - 33.2 mg, raspberry flavor - 0.4 mg, citric acid monohydrate - 0.058 mg, sodium citrate - 0.022 mg, polysorbate 80 - 0.4 mg, methyl parahydroxybenzoate - 0.184 mg, propyl parahydroxybenzoate - 0.02 mg, purified water - up to 0.2 ml.

Grammidin® is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Grammidin® Valenta Russia spray
Grammidin® Valenta Russia lozenges

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Grammidin®

Dosage and Administration

Locally, by spraying the mucous membrane of the mouth and throat. It is applied after food.

Dosage for adults: 4 injections per application 3 times a day for 7 days. Immediately after the use of the drug should refrain from eating and drinking for 1 hour.

If there is no improvement after treatment, or symptoms become worse, or new symptoms appear, you should consult your doctor.

Use the drug only according to the indications, the method of application and in the doses specified in the instructions.

Adverse reactions

Allergic reactions to the components of the drug.

If you have side effects indicated in the instructions, or they get worse, or you notice any other side effects not mentioned in the instructions, inform your doctor.

Contraindications

Hypersensitivity to the components of the drug

Drug interactions

Currently not described cases of clinically significant interactions with other drugs.

Overdosage

Symptoms: the use of the drug in doses exceeding the recommended, can cause disorders of the gastrointestinal tract: nausea, vomiting, diarrhea. Treatment: should stop using the drug and consult a doctor.

  • Brand name: Grammidin®
  • Active ingredient: Gramicidin C, Cetylpyridinium Chloride
  • Dosage form: Dosed topical spray.
  • Manufacturer: Rottapharm

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