Prontosan®
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2019-09-19
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Clinical Pharmacology
The sterile solution "Prontosan" is a ready-to-use medication for antimicrobial action. The main components that delay the development of microbes are undecylen-midopropyl betaine (surfactant) and modern antiseptic - polyhexanide (polyaminopropyl biguanide). These substances are dissolved in ordinary distilled water. "Prontosan" actively prevents the reproduction of a large number of types of pathogens / microorganisms contributing to toxicity, such as Pseudomonas aeruginosa, St. Epidermidis, E. coli, MRSA, St. Aureus, etc.
Indications
Prontosan wound solution can be used to wash and cleanse:
- purulent-necrotic wounds of various origin, including non-healing wounds, such as trophic ulcers, pressure sores, etc .;
- post-traumatic injuries (abrasions, bruises, cuts, etc.);
- postoperative wounds;
- thermal and chemical burns;
- wound surfaces around stomas, catheters or probes.
Prontosan solution can be used to clean the wound surface during the primary surgical treatment of injuries of the upper and lower extremities.
Prontosan solution can be used for dressings to moisturize wound dressings, gauze wipes, turundas, etc., to remove them without damaging the wound surface.
Prontosan® is marketed under different brands and generic names, and comes in different dosage forms:
| Brand name | Manufacturer | Country | Dosage form |
|---|---|---|---|
| Prontosan | B. Brown Medical AG | Germany | solution |
| Prontosan | B. Brown Medical AG | Germany | gel |
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Dosage and Administration
The surface of the wound must be thoroughly washed and cleaned with the help of Prontosan solution to remove foreign and necrotic tissues, exudate, surface films and crusts, fibrin and biofilms.
In order to reduce the risk of microbial incursion into the wound, it is recommended to clean as much of the area around the wound as possible with the help of Prontosan solution.
Gauze cloths or other types of dressings soaked in Prontosan solution can be used to cleanse and moisten the surface of the wound in accordance with their instructions. Due to the relatively small water-holding capacity of the solution (unlike Prontosan gel), dressings should be performed at least once a day, and preferably several times a day.
To remove abundant accumulations of fibrin, denser films, crusts, scab, etc. It is recommended to continue the treatment of the wound with Prontosan gel.
Washing of the wound with the Prontosan solution should be carried out with a frequency that is sufficient to completely remove all films and necrotic tissues and achieve optimal cleansing of the wound to accelerate its healing or for the subsequent stage of surgical treatment.
For washing large wound surfaces, as well as wounds in hard-to-reach places, it is recommended that the whole affected organ or part of the body be treated with Prontosan for at least 15 minutes.
Prontosan solution can be warmed to body temperature immediately before use.
Adverse reactions
Seldom: a slight burning sensation that disappears in a few minutes.
Contraindications
Individual intolerance to the components of the drug.
Avoid contact with eyes and hyaline cartilage; thoroughly rinse with saline in case of contact.
Drug interactions
Prontosan should not be mixed and used together with other disinfectants, ointments, oils, surfactants, enzymes, etc.
Special instructions
Prontosan does not have allergenic and irritating properties, painlessly applied to the wound surface, does not inhibit the development of granulations and does not prevent epithelialization of the wound.
To avoid reinfection of the wound, vials directly touching the wound surface should be discarded immediately after use.
- Brand name: Prontosan
- Active ingredient: Unicyclic Amidopropyl Betaine
- Manufacturer: B. Brown Medical AG
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