Prednisolone
Biosynthesis
1164 Items
2019-09-19
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Clinical Pharmacology
Prednisolone has anti-inflammatory, antiallergic, antipruritic and antiexudative action.
Reduces the formation, release and activity of inflammatory mediators (histamine, kinin, lysosomal enzymes). Suppresses cell migration to the site of inflammation; reduces vasodilation and increased vascular permeability in the inflammation. Reduces exudation due to vasoconstrictor action.
Suppresses the action of macrophages, target cells, cytokines, which are involved in the development of the reaction in the form of allergic contact dermatitis. Prevents access of sensitized T-lymphocytes and macrophages to target cells.
Indications
Used in the treatment of inflammatory and allergic skin diseases of non-microbial etiology: eczema, allergic, seborrheic and contact dermatitis, neurodermatitis, psoriasis, lupus erythematosus, erythroderma.
Composition
Active substance: prednisone - 0.5 g Excipients: distilled glycerin, medical vaseline, stearic acid, emulsifier No. 1, nipagin, nipazol, purified water.
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