Theraflex Advance

Brand Bayer Pharma AG

In stock 1919 Items

Available since: 2019-09-19

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Clinical Pharmacology

Teraflex is a modern chondroprotector that contains related cartilage tissue of the joints - Glucosamine and Chondroitin. Due to this composition, Teraflex contributes to the renewal of cartilage tissue, helps reduce pain and improve joint mobility, and also prevents further development of the disease.

Treatment is recommended to start with the drug Teraflex Advance, which quickly reduces pain and at the same time begins to stimulate the renewal of cartilage tissue.

Teraflex Advance is a combined preparation containing chondroitin sulfate, glucosamine sulfate and ibuprofen as active ingredients.

Then it is advisable to take Teraflex to extend the analgesic effect and protect the cartilage.

Indications

Accompanied by moderate pain: osteoarthritis of the large joints; osteocondritis of the spine.

Composition

1 capsule contains:

Active substances: glucosamine sulfate - 250 mg; chondroitin sodium sulfate - 200 mg; ibuprofen - 100 mg.

Excipients: MCC - 30.78 mg; corn starch - 19.69 mg; pregelatinized starch - 17.47 mg; stearic acid - 11.59 mg; sodium carboxymethyl starch - 10 mg; Crospovidone - 10 mg; magnesium stearate - 3 mg; silicon dioxide - 4.05 mg; Povidone - 2.382 mg.

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Dosage and Administration

Orally, washing down with a small amount of water.

Adults - 2 caps. 3 times a day after meals. The duration of admission without consulting a doctor should not exceed 3 weeks. Further use of the drug should be agreed with the doctor.

Adverse reactions

When using the drug Teraflex Advance, nausea, abdominal pain, flatulence, diarrhea, constipation, allergic reactions are possible. These reactions disappear after drug withdrawal.

Consideration should be given to the possibility of adverse reactions associated with ibuprofen present in the preparation. When using ibuprofen at higher doses than the Teraflex Advance contains, the undesirable effects listed below can occur.

From the digestive tract: NSAID-gastropathy (abdominal pain, nausea, vomiting, heartburn, loss of appetite, diarrhea, flatulence, constipation; rarely - ulceration of the gastrointestinal mucosa, which in some cases are complicated by perforation and bleeding); irritation or dryness of the oral mucosa, pain in the mouth, ulceration of the mucous membrane of the gums, aphthous stomatitis, pancreatitis.

From the hepatobiliary system: hepatitis.

On the part of the respiratory system: shortness of breath, bronchospasm.

From the senses: hearing impairment (hearing loss, ringing or tinnitus), visual impairment (toxic damage to the optic nerve, blurred vision or double vision, scotoma, dryness and irritation of the eyes, conjunctival edema, and age of allergic genesis).

From the side of the central nervous system and peripheral nervous system: headache, dizziness, insomnia, anxiety, nervousness and irritability, psychomotor agitation, drowsiness, depression, confusion, hallucinations; rarely, aseptic meningitis (more often in patients with autoimmune diseases).

From the CCC: heart failure, tachycardia, increased blood pressure.

From the urinary system: acute renal failure, allergic nephritis, nephrotic syndrome (edema), polyuria, cystitis.

Allergic reactions: skin rash (typically erythematous or urticaria), pruritus, angioedema, anaphylactoid reactions, anaphylactic shock, bronchoconstriction or dyspnea, fever, erythema multiforme (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), eosinophilia, allergic rhinitis.

From the side of blood-forming organs: anemia (including hemolytic, aplastic), thrombocytopenia and thrombocytopenic purpura, agranulocytosis, leukopenia.

Laboratory indicators: bleeding time may increase, serum glucose concentration may decrease, creatinine clearance may decrease; hematocrit or hemoglobin may decrease; serum creatinine concentration may increase; hepatic transaminase activity may increase.

Contraindications

Hypersensitivity to any of the ingredients that make up the drug;
hypersensitivity to acetylsalicylic acid or other NSAIDs in history;
erosive and ulcerative diseases of the gastrointestinal tract (including peptic ulcer of the stomach and duodenum in the acute stage, Crohn's disease, ulcerative colitis);
aspirin asthma;
hemophilia and other bleeding disorders (including hypocoagulation);
hemorrhagic diathesis;
gastrointestinal bleeding;
intracranial hemorrhage;
pregnancy;
lactation period;
children's age up to 12 years.

Pregnancy and Lactation

Contraindicated in pregnancy and lactation.

Special instructions

During long-term treatment, it is necessary to control the picture of peripheral blood and the functional state of the liver and kidneys.

At the onset of symptoms of gastropathy, careful monitoring is shown, including esophagogastroduodenoscopy, blood analysis with hemoglobin, hematocrit, fecal occult blood analysis.

If necessary, the simultaneous reception of additional NSAIDs and analgesic drugs, the doctor should consider the presence in the drug ibuprofen. If long-term supplementation with additional NSAIDs is necessary, Teraflex, which does not contain ibuprofen, should be used.

If necessary, determine the 17-ketosteroids drug should be canceled 48 hours before the study.

During treatment, alcohol is not recommended.

Impact on the ability to drive vehicles and other mechanisms that require high concentration of attention

Patients should refrain from activities requiring increased attention, quick mental and motor responses.