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Restores impaired immunological reactivity: regulates the number and ratio of T-and B-lymphocytes and their subpopulations stimulates cellular immunity reactions, enhances phagocytosis; stimulates the processes of regeneration and blood formation in case of their oppression, and also improves the course of the processes of cellular metabolism.
- Immunodeficiency states in adults and children (from 6 months to 14 years) with: infectious purulent and septic processes. Persistent dysfunction of the thymus: radiation sickness, thymus tumors, prompt removal of the thymus.
- Acute and chronic viral and bacterial infections.
- Violation of regenerative processes.
- Immunosuppression and hematopoiesis after chemotherapy or radiation therapy in cancer patients.
1 bottle contains:
Active substance: thymic polypeptides - 10 mg.
Excipients: glycine - 20 mg.
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Dosage and Administration
Taktivin is injected s / c; in adults, 1 ml of a 0.01% solution (which is 40 mcg / m2 or 1–2 mcg / kg) is administered at night, once a day, daily for 5–14 days. If necessary, the course of treatment is continued for 1 month in 2 ml every 3rd day. The course of treatment can be repeated in 2–3 weeks.
For children from 6 months to 14 years, Taktivin is prescribed s / c at the rate of 2–3 mcg per 1 kg of body weight.
With frequent diseases of acute respiratory viral infections, acute respiratory infections, purulent-septic infections, with atopic dermatitis complicated by the herpes virus, Taktivin is administered daily for 7–10 days in combination with basic drugs. Subsequent administration of the drug - 1 injection every other day for 1-2 weeks. It is recommended to enter in the evening between the 17th and 20th hours.
Hyperimmune cytolysis provocation. Exacerbation of purulent infections.
- Lactation period.
Pregnancy and Lactation
Use of the drug is contraindicated in pregnancy.
- Brand name: Timalin
- Active ingredient: Thymus extract
- Dosage form: Lyophilisate for preparation of solution for intramuscular administration.
- Manufacturer: Samson-Med OAO
- Country of Origin: Russia
- A Theoretical Structural Study of Isoniazid Complexes with Thiotriazoline
- Distribution of the hormonal thymic factor thymalin in human fetal tissues
- Effect of thymalin on the cyclic nucleotide system in the mouse spleen
- Effect of thymalin on some immunologic parameters and on uterine structure and function in guinea pigs with endometrial hyperplasia
- Interaction between thymalin and lymphocytes from different sources in experimentsin vivoandin vitro
- Morphological changes in the thymus after thymalin administration in experimental osteomyelitis
- Effect of thymalin on thymus morphology and function in mice
- Effect of thymalin on the state of the blood kallikrein-kinin system in thymectomized rats
- Extrathymic distribution of thymalin-positive cells in epithelia of organs close to the thymus morphogenetically during human prenatal development
- Dynamics of thymalin localization in human embryonic thymus tissues
- Effect of vitamin E and thymalin on the development of experimental allergic encephalomyelitis
- Effect of thymalin on protein synthesis in the brain and on conditionedreflex activity of the offspring of neurosensitized rats
- Effect of thymalin and heterologous transfusion on blood clotting and fibrinolysis in thymectomized rats
- Effects of thymalin and α-tocopherol on morphofunctional state of neuroendocrine system at the early stages of atherogenesis
- Correction of hyperlipoproteinogenic microangiopathy and organ pathology with thymalin and leu-enkephalin in the early stages of atherogenesis
- Levels of the thymic factor thymalin in human and murine skin epithelia during ontogeny
- Age- and sex-related differences of hypothalamic neuroendocrine center response to α-tocopherol acetate and thymalin preparation
- Age-Related Changes of Thymalin Content in Human Epidermis
- Thymalin in Developing Respiratory Organs of Human Fetus
- Effect of Thymalin on the Tumor and Thymus under Conditions of Activation Therapy In Vivo