Karipazim
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Clinical Pharmacology
KARIPASIM has proteolytic activity. The drug cleaves necrotic tissue, thins viscous secretions, exudates, blood clots .. By its action, karypazim is close to chymotrypsin and trypsin.
Indications
Caripazim is used for third-degree burns as a means to accelerate the rejection of scabs and cleanse granulating wounds from residues of purulent-necrotic tissues.
Composition
Active ingredients: papain, chymopapain A, chymopapain B, peptidase A, peptidase B, lysocin.
Karipazim is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Karipazim | MedFlorin | Russia | vials |
Karipazim | MedFlorin | Russia | bottle |
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Dosage and Administration
Caripazim is applied topically in the form of 0.5%, 1% or 2% solutions, depending on the scab thickness. Solutions are prepared ex tempore 0.5% solution of novocaine or isotonic sodium chloride solution. The napkin moistened with the preparation is placed on the burn surface, covered with a moisture-proof bandage. At the same time process no more than 30% of the total surface of the body. The dressing is changed 1 time per day or 1 time in 2 days, while removing the detached necrotic tissue. The course of treatment from 4 to 12 days.
Adverse reactions
Allergic reactions.
Contraindications
- pregnancy, lactation;
- increased individual sensitivity to the drug.
Drug interactions
There is no established clinically significant interaction of caripazim with other drugs.
Special instructions
The drug Karipazim does not adversely affect the ability to drive a car and work with mechanisms.
- Brand name: Karipazim
- Active ingredient: Papaya Milky Ssk
- Dosage form: Powder for the preparation of the solution.
- Manufacturer: MedFlorin
- Country of Origin: Russia